Integrating research during the outbreak response is not only essential to prepare for future outbreaks, it is also an ethical obligation to help improve patient care in current crises.
  • Identification of research priorities
  • Stimulation and coordination of research projects
  • Response to call for proposal for funding
  • Provision of methodological, data and statistical centers
  • Support to ethic and regulatory compliance
  • Connecting health authorities and researchers
Since 2013 REACTing has coordinated the French research response during several infectious disease epidemics.

Key facts

 

On December 31, 2019, the first suspected cases of an epidemic of viral pneumonia of unknown etiology was reported in the city of Wuhan, China (about 11 million inhabitants). The initial patient cluster was linked to the wholesale market of Huanan Seafood, selling fish and other animals. This market has been closed on January 1, 2020. Thus, the hypothesis of a zoonosis with a reservoir of animal origin was issued at the start of the epidemic. The pathogen is a new coronavirus, called 2019-nCoV. On January 7, 2020 the Chinese health authorities and the World Health Organization (WHO) announced officially the discovery of the novel coronavirus. Two days later, on January 9, 2020, the Chinese authorities reported the first death. WHO officially confirmed human-to-human transmission of the virus on January 23, 2020. The initial Wuhan cluster included 41 patients, confirmed after a specific PCR test. On January 30, WHO declared a Public Health Emergency of International Concern (PHEIC).

 

For updated figures, John Hopkins University developed a great interactive map.

Agnès Buzyn announces the first three French cases on January 24, 2020. These are the first European cases.

For specific updates on French cases, please consult Santé Publique France.

 

The role of REACTing : coordinating French research response

 

① Since the beginning of the 2019-nCoV outbreak, REACTing is playing a key role in the coordination and information sharing regarding 2019-nCoV outbreak in France by :

□ Closely monitoring the situation and encouraging data sharing

 

□ Promoting good practices and standardization of data collection in clinical research

 

□ Provide comprehensive information for decision-makers, the media and the public

 

②REACTing coordinates French research response to this 2019-nCoV and organizes fundraising involving key public stakeholders

Few examples of 2019-nCoV related research projects supported by REACTing :

□ Modeling and anticipation of import risk in Europe

□ Therapeutic targets, monoclonal antibodies and vaccine candidates

□ Observational follow-up study of patients infected with 2019-nCoV and cases contact

□ Pharmacokinetic and pharmacodynamic study (PK / PD) of patients

□ Social sciences project

 

 

Ressources

 

  1. Scientific papers

 

  1. Online tools

 

  1. Useful links